Landmark study confirms CBD reduces seizures in children suffering from Dravet Syndrome. A rare drug-resistant form of epilepsy with a high mortality rate.
Dravet Syndrome is a rare and potentially deadly form of epilepsy that is associated with high mortality and drug resistant seizures. Epileptic episodes can last as long as ten minutes at a time.
This life threatening disease starts at infancy. Symptoms often become noticeable within the first year of birth.
What makes this form of epilepsy so dangerous are the seizures that can more than two minutes. Episodes over thirty minutes can result in disability and even death.
It is reported that only 1 out of 20,000 – 40,000 children develop Dravet syndrome. People diagnosis with this disease face a 20 to 30 percent chance of mortality.
The gene SCN1A provides the instructions needed to create sodium pathways for cells. Sodium channels created by SCN1A are found in the muscles and brain.
The pathways are used to send sodium atoms into cells, controlling voltage and signaling. The sodium atoms carry a positive charge that is responsible for transmitting signals between neurons.
Without them the brain is unable to function correctly. This causes miscommunication between neurons in the brain and muscle.
CBD Proven to Reduced the Frequency of Seizures
120 children from the ages of 2 to 18 had enrolled in this ground breaking study. All of the 120 children involved had been diagnosed with Dravents and drug resistant seizures.
The entire study had taken 14 weeks. For the first 4 weeks no CBD was administered , only the current medications. The purpose of this 4 week period was to collect data and create a seizure frequency baseline.
The study compared the results of a double blind trial in which randomly chosen children added CBD to the normal medication regime. The other children were given a placebo for control and comparison.
This study confirmed without doubt that cannabis reduced seizure frequency. On average, the the children in the group had 12.4 seizures per month. The patients that took Cannabidiol or CBD had decreased to 5.9 seizures per month.
Compare this to the placebo group which had a slight decease of less than 1%. Its easy to see how effective CBD is for treating epileptic seizures.
The Cannabinoid CBD
Among the many cannabinoid contained in Cannabis, CBD seems to be getting the most attention. Its also important to know that CBD does not get you high. This makes it the perfect candidate for treating epilepsy in children.
But this does not mean other Cannabinoid like THC, don’t carry medicinal benefits. This is just more evidence in the side of legalization. Since the DEA has THC listed as a controlled substance that is under restriction, making it almost impossible to study and document in medical journals.
If the government was to make Marijuana legal at the federal level, more studies would be done.
- SCN1A Gene: https://ghr.nlm.nih.gov/gene/SCN1A
- Research Results: http://www.nejm.org/doi/full/10.1056/NEJMoa1611618